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Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria

Carbon-negative synthesis of biochemical products has the potential to mitigate global CO(2) emissions. An attractive route to do this is the reverse β-oxidation (r-BOX) pathway coupled to the Wood-Ljungdahl pathway. Here, we optimize and implement r-BOX for the synthesis of C4-C6 acids and alcohols...

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Detalles Bibliográficos
Autores principales:	Vögeli, Bastian, Schulz, Luca, Garg, Shivani, Tarasava, Katia, Clomburg, James M., Lee, Seung Hwan, Gonnot, Aislinn, Moully, Elamar Hakim, Kimmel, Blaise R., Tran, Loan, Zeleznik, Hunter, Brown, Steven D., Simpson, Sean D., Mrksich, Milan, Karim, Ashty S., Gonzalez, Ramon, Köpke, Michael, Jewett, Michael C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160091/ https://www.ncbi.nlm.nih.gov/pubmed/35650184 http://dx.doi.org/10.1038/s41467-022-30571-6

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