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A Novel Faster-Acting, Dry Powder-Based, Naloxone Intranasal Formulation for Opioid Overdose

OBJECTIVE: To examine the pharmacokinetics and safety of FMXIN001, a new intranasal powder-based naloxone formulation, in comparison to Narcan® nasal liquid spray. METHODS: FMXIN001, was developed by blending drug microspheres with larger lactose monohydrate particles, that serve as diluent and carr...

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Detalles Bibliográficos
Autores principales: Lapidot, Tair, Bouhajib, Mohammed, Faulknor, Janice, Khan, Shabaz, Krayz, Galia Temtsin, Abrutzky, Carolina, Megiddo, Dalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160115/
https://www.ncbi.nlm.nih.gov/pubmed/35386013
http://dx.doi.org/10.1007/s11095-022-03247-5