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Beclin1 haploinsufficiency compromises mesenchymal stem cell-offered cardioprotection against myocardial infarction

Mesenchymal stem cells (MSCs)-based therapy has displayed some promises in ischemia heart diseases although its efficacy may be affected by changes in surrounding environments. This study evaluated the role of autophagy insufficiency using Beclin1 haploinsufficiency (BECN(+/−)) on intra-myocardial M...

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Detalles Bibliográficos
Autores principales: Qin, Xing, Fei, Juanjuan, Duan, Yu, Ceylan, Asli F., Zhang, Fuyang, Ren, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160171/
https://www.ncbi.nlm.nih.gov/pubmed/35650374
http://dx.doi.org/10.1186/s13619-022-00121-y