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Inferring Tissue-Specific, TLR4-Dependent Type 17 Immune Interactions in Experimental Trauma/Hemorrhagic Shock and Resuscitation Using Computational Modeling

Trauma/hemorrhagic shock followed by resuscitation (T/HS-R) results in multi-system inflammation and organ dysfunction, in part driven by binding of damage-associated molecular pattern molecules to Toll-like Receptor 4 (TLR4). We carried out experimental T/HS-R (pseudo-fracture plus 2 h of shock fol...

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Detalles Bibliográficos
Autores principales:	Shah, Ashti M., Zamora, Ruben, Korff, Sebastian, Barclay, Derek, Yin, Jinling, El-Dehaibi, Fayten, Billiar, Timothy R., Vodovotz, Yoram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160183/ https://www.ncbi.nlm.nih.gov/pubmed/35663944 http://dx.doi.org/10.3389/fimmu.2022.908618

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