Cargando…

Short chain fatty acids-producing and mucin-degrading intestinal bacteria predict the progression of early Parkinson’s disease

To elucidate the relevance of gut dysbiosis in Parkinson’s disease (PD) in disease progression, we made random forest models to predict the progression of PD in two years by gut microbiota in 165 PD patients. The area under the receiver operating characteristic curves (AUROCs) of gut microbiota-base...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nishiwaki, Hiroshi, Ito, Mikako, Hamaguchi, Tomonari, Maeda, Tetsuya, Kashihara, Kenichi, Tsuboi, Yoshio, Ueyama, Jun, Yoshida, Takumi, Hanada, Hiroyuki, Takeuchi, Ichiro, Katsuno, Masahisa, Hirayama, Masaaki, Ohno, Kinji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160257/ https://www.ncbi.nlm.nih.gov/pubmed/35650236 http://dx.doi.org/10.1038/s41531-022-00328-5

Ejemplares similares

Gut microbiota in dementia with Lewy bodies
por: Nishiwaki, Hiroshi, et al.
Publicado: (2022)

Intestinal Collinsella may mitigate infection and exacerbation of COVID-19 by producing ursodeoxycholate
por: Hirayama, Masaaki, et al.
Publicado: (2021)

Short-Chain Fatty Acid-Producing Gut Microbiota Is Decreased in Parkinson’s Disease but Not in Rapid-Eye-Movement Sleep Behavior Disorder
por: Nishiwaki, Hiroshi, et al.
Publicado: (2020)

Effects of Pesticide Intake on Gut Microbiota and Metabolites in Healthy Adults
por: Ueyama, Jun, et al.
Publicado: (2022)

Gastrointestinal disorders in Parkinson’s disease and other Lewy body diseases
por: Hirayama, Masaaki, et al.
Publicado: (2023)

Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles -
por: Ichihara, Masatoshi, et al.
Publicado: (2015)

Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson’s disease in rats
por: Ito, Mikako, et al.
Publicado: (2012)

Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease
por: Hirayama, Masaaki, et al.
Publicado: (2019)

Quantification of hydrogen production by intestinal bacteria that are specifically dysregulated in Parkinson's disease
por: Suzuki, Anzu, et al.
Publicado: (2018)

Progression of Parkinson's disease is associated with gut dysbiosis: Two-year follow-up study
por: Minato, Tomomi, et al.
Publicado: (2017)

Safety and tolerability of aripiprazole in patients with psychosis associated with Parkinson's disease—Results of a multicenter open trial
por: Kashihara, Kenichi, et al.
Publicado: (2022)

Secreted Signaling Molecules at the Neuromuscular Junction in Physiology and Pathology
por: Ohkawara, Bisei, et al.
Publicado: (2021)

Molecular Hydrogen as an Emerging Therapeutic Medical Gas for Neurodegenerative and Other Diseases
por: Ohno, Kinji, et al.
Publicado: (2012)

A latent allocation model for the analysis of microbial composition and disease
por: Abe, Ko, et al.
Publicado: (2018)

ENIGMA: an enterotype-like unigram mixture model for microbial association analysis
por: Abe, Ko, et al.
Publicado: (2019)

Hierarchical non-negative matrix factorization using clinical information for microbial communities
por: Abe, Ko, et al.
Publicado: (2021)

Clinical and Imaging Features of Multiple System Atrophy: Challenges for an Early and Clinically Definitive Diagnosis
por: Watanabe, Hirohisa, et al.
Publicado: (2018)

Real‐World Nonmotor Changes in Patients with Parkinson's Disease and Motor Fluctuations: J‐FIRST
por: Watanabe, Hirohisa, et al.
Publicado: (2020)

Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions
por: Ishigaki, Shinsuke, et al.
Publicado: (2012)

FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD
por: Fujioka, Yusuke, et al.
Publicado: (2013)

The ALS/FTLD-related RNA-binding proteins TDP-43 and FUS have common downstream RNA targets in cortical neurons()
por: Honda, Daiyu, et al.
Publicado: (2013)

ERRATUM: FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD
por: Fujioka, Yusuke, et al.
Publicado: (2013)

ERRATUM: Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions
por: Ishigaki, Shinsuke, et al.
Publicado: (2013)

Corrigendum to “The ALS/FTLD-related RNA-binding proteins TDP-43 and FUS have common downstream RNA targets in cortical neurons” [FEBS Open Bio 4 (2014) 1–10]
por: Honda, Daiyu, et al.
Publicado: (2014)

AG-dependent 3′-splice sites are predisposed to aberrant splicing due to a mutation at the first nucleotide of an exon
por: Fu, Yuan, et al.
Publicado: (2011)

Differential effects of spinal motor neuron-derived and skeletal muscle-derived Rspo2 on acetylcholine receptor clustering at the neuromuscular junction
por: Li, Jin, et al.
Publicado: (2018)

Lansoprazole Upregulates Polyubiquitination of the TNF Receptor-Associated Factor 6 and Facilitates Runx2-mediated Osteoblastogenesis
por: Mishima, Kenichi, et al.
Publicado: (2015)

Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies
por: Ito, Mikako, et al.
Publicado: (2011)

Impaired Pain Processing Correlates with Cognitive Impairment in Parkinson's Disease
por: Okada, Akinori, et al.
Publicado: (2016)

Molecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein Response
por: Hasegawa, Tomoya, et al.
Publicado: (2022)

Meclozine Facilitates Proliferation and Differentiation of Chondrocytes by Attenuating Abnormally Activated FGFR3 Signaling in Achondroplasia
por: Matsushita, Masaki, et al.
Publicado: (2013)

Identification of Qk as a Glial Precursor Cell Marker that Governs the Fate Specification of Neural Stem Cells to a Glial Cell Lineage
por: Takeuchi, Akihide, et al.
Publicado: (2020)

Verapamil Protects against Cartilage Degradation in Osteoarthritis by Inhibiting Wnt/β-Catenin Signaling
por: Takamatsu, Akira, et al.
Publicado: (2014)

Primary Borderline Mucinous Tumors of the Testis: A Case Report and Literature Review
por: Funada, Satoshi, et al.
Publicado: (2015)

Ovarian mucinous adenocarcinoma with functioning stroma in postmenopausal women: aromatase and SF-1 expressions
por: Hattori, Yuka, et al.
Publicado: (2015)

Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome
por: Bian, Yang, et al.
Publicado: (2009)

Neural Isoforms of Agrin Are Generated by Reduced PTBP1−RNA Interaction Network Spanning the Neuron−Specific Splicing Regions in AGRN
por: Bushra, Samira, et al.
Publicado: (2023)

Acute necrotizing calculous cholecystitis after treatment with ceftriaxone in an elderly patient: a case report
por: Shigemori, Tsunehiko, et al.
Publicado: (2022)

Development of machine learning models for predicting unfavorable functional outcomes from preoperative data in patients with chronic subdural hematomas
por: Fuse, Yutaro, et al.
Publicado: (2023)

Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells
por: Iio, Akio, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_29rd87q4anaf21d8nf72l5vikc