Derivation of totipotent-like stem cells with blastocyst-like structure forming potential

It is challenging to derive totipotent stem cells in vitro that functionally and molecularly resemble cells from totipotent embryos. Here, we report that a chemical cocktail enables the derivation of totipotent-like stem cells, designated as totipotent potential stem (TPS) cells, from 2-cell mouse e...

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Detalles Bibliográficos
Autores principales: Xu, Yaxing, Zhao, Jingru, Ren, Yixuan, Wang, Xuyang, Lyu, Yulin, Xie, Bingqing, Sun, Yiming, Yuan, Xiandun, Liu, Haiyin, Yang, Weifeng, Fu, Yenan, Yu, Yu, Liu, Yinan, Mu, Rong, Li, Cheng, Xu, Jun, Deng, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160264/
https://www.ncbi.nlm.nih.gov/pubmed/35508506
http://dx.doi.org/10.1038/s41422-022-00668-0

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