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Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT

PURPOSE: To compare the predicted ablation depth (AD) with the postoperatively measured corneal ablation depth (postop-AD) at central, paracentral, and midperipheral locations using two rotating Scheimpflug analyzers and a Fourier-domain optical coherence tomographer in eyes that underwent femtoseco...

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Autores principales: Chen, Hao, Wang, Ziqian, Li, Kunke, Wang, Yiran, Li, Xin, Du, Lan, Lin, Meimin, Savini, Giacomo, Wang, Qinmei, Yu, Ayong, Chen, Sisi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160334/
https://www.ncbi.nlm.nih.gov/pubmed/35665335
http://dx.doi.org/10.3389/fmed.2022.907334
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author Chen, Hao
Wang, Ziqian
Li, Kunke
Wang, Yiran
Li, Xin
Du, Lan
Lin, Meimin
Savini, Giacomo
Wang, Qinmei
Yu, Ayong
Chen, Sisi
author_facet Chen, Hao
Wang, Ziqian
Li, Kunke
Wang, Yiran
Li, Xin
Du, Lan
Lin, Meimin
Savini, Giacomo
Wang, Qinmei
Yu, Ayong
Chen, Sisi
author_sort Chen, Hao
collection PubMed
description PURPOSE: To compare the predicted ablation depth (AD) with the postoperatively measured corneal ablation depth (postop-AD) at central, paracentral, and midperipheral locations using two rotating Scheimpflug analyzers and a Fourier-domain optical coherence tomographer in eyes that underwent femtosecond laser-assisted LASIK (FS-LASIK). METHODS: The values of corneal thickness were measured preoperatively and postoperatively at one and three months. The difference between preoperative and postoperative was defined as postop-AD. Measurements were performed at the corneal vertex and mid-peripheral area. The mid-peripheral corneal thickness was measured at the superior, inferior, nasal, and temporal locations at a distance of 1.0 or 2.5 mm from the corneal vertex. The predicted AD was calculated by ORK-CAM software (Schwind eye tech-solutions GmbH, Kleinostheim, Germany), and the difference between the predicted AD and postop-AD was defined as Δ-AD. Paired t-test analysis was employed to evaluate the differences, agreement was assessed by the Bland-Altman method. RESULTS: Forty-two eyes of 42 patients were investigated. At one month, the predicted AD in the central and paracentral areas was underestimated by the Pentacam HR (Oculus, Wetzlar, Germany), Sirius (Costruzione Strumenti Oftalmici, Florence, Italy) and RTVue OCT (Optovue Inc., Freemont, CA, United States), whereas Δ-AD was negative as established by all devices and predominantly statistically significant. The Δ-AD values approximated zero at three months. The mean difference of Δ-AD at three months at the corneal vertex was 0.67 ± 9.39 mm, −7.92 ± 9.05 mm and −1.36 ± 8.31 mm, respectively. The mid-peripheral measurements had positive values at one month and even more highly positive at three months (with statistically significant differences in most of the cases). The agreement between the predicted and postop-AD was moderate with all devices, but slightly better with RTVue. CONCLUSION: The predicted AD seems to be underestimated in the central and paracentral corneal area and overestimated in the mid-periphery. TRANSLATIONAL RELEVANCE: The study could help to partly explain and prevent the refractive errors after FS-LASIK.
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spelling pubmed-91603342022-06-03 Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT Chen, Hao Wang, Ziqian Li, Kunke Wang, Yiran Li, Xin Du, Lan Lin, Meimin Savini, Giacomo Wang, Qinmei Yu, Ayong Chen, Sisi Front Med (Lausanne) Medicine PURPOSE: To compare the predicted ablation depth (AD) with the postoperatively measured corneal ablation depth (postop-AD) at central, paracentral, and midperipheral locations using two rotating Scheimpflug analyzers and a Fourier-domain optical coherence tomographer in eyes that underwent femtosecond laser-assisted LASIK (FS-LASIK). METHODS: The values of corneal thickness were measured preoperatively and postoperatively at one and three months. The difference between preoperative and postoperative was defined as postop-AD. Measurements were performed at the corneal vertex and mid-peripheral area. The mid-peripheral corneal thickness was measured at the superior, inferior, nasal, and temporal locations at a distance of 1.0 or 2.5 mm from the corneal vertex. The predicted AD was calculated by ORK-CAM software (Schwind eye tech-solutions GmbH, Kleinostheim, Germany), and the difference between the predicted AD and postop-AD was defined as Δ-AD. Paired t-test analysis was employed to evaluate the differences, agreement was assessed by the Bland-Altman method. RESULTS: Forty-two eyes of 42 patients were investigated. At one month, the predicted AD in the central and paracentral areas was underestimated by the Pentacam HR (Oculus, Wetzlar, Germany), Sirius (Costruzione Strumenti Oftalmici, Florence, Italy) and RTVue OCT (Optovue Inc., Freemont, CA, United States), whereas Δ-AD was negative as established by all devices and predominantly statistically significant. The Δ-AD values approximated zero at three months. The mean difference of Δ-AD at three months at the corneal vertex was 0.67 ± 9.39 mm, −7.92 ± 9.05 mm and −1.36 ± 8.31 mm, respectively. The mid-peripheral measurements had positive values at one month and even more highly positive at three months (with statistically significant differences in most of the cases). The agreement between the predicted and postop-AD was moderate with all devices, but slightly better with RTVue. CONCLUSION: The predicted AD seems to be underestimated in the central and paracentral corneal area and overestimated in the mid-periphery. TRANSLATIONAL RELEVANCE: The study could help to partly explain and prevent the refractive errors after FS-LASIK. Frontiers Media S.A. 2022-05-19 /pmc/articles/PMC9160334/ /pubmed/35665335 http://dx.doi.org/10.3389/fmed.2022.907334 Text en Copyright © 2022 Chen, Wang, Li, Wang, Li, Du, Lin, Savini, Wang, Yu and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Chen, Hao
Wang, Ziqian
Li, Kunke
Wang, Yiran
Li, Xin
Du, Lan
Lin, Meimin
Savini, Giacomo
Wang, Qinmei
Yu, Ayong
Chen, Sisi
Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT
title Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT
title_full Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT
title_fullStr Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT
title_full_unstemmed Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT
title_short Agreement Between Predicted and Actual Measured Ablation Depth After FS-LASIK Using Different Rotating Scheimpflug Cameras and OCT
title_sort agreement between predicted and actual measured ablation depth after fs-lasik using different rotating scheimpflug cameras and oct
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160334/
https://www.ncbi.nlm.nih.gov/pubmed/35665335
http://dx.doi.org/10.3389/fmed.2022.907334
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