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Sirtuin Type 1 Mediates the Antidepressant Effect of S-Ketamine in a Chronic Unpredictable Stress Model

BACKGROUND: Major depressive disorder (MDD) refers to a mental disease with complex pathogenesis and treatment mechanism. S-ketamine exhibited high effectiveness in treating MDD. However, the pharmacological activity of S-ketamine has not been reported yet. MATERIALS AND METHODS: In this study, depr...

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Detalles Bibliográficos
Autores principales:	Hou, Lanwei, Miao, Jingyu, Meng, Haiwei, Liu, Xiao, Wang, Di, Tan, Yawen, Li, Chuangang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160425/ https://www.ncbi.nlm.nih.gov/pubmed/35664490 http://dx.doi.org/10.3389/fpsyt.2022.855810

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