Mesenchymal Stem Cells Improve Cognitive Impairment and Reduce Aβ Deposition via Promoting AQP4 Polarity and Relieving Neuroinflammation in Rats With Chronic Hypertension-Induced Cerebral Small-Vessel Disease

Cerebral small-vessel disease (CSVD) is the main cause of vascular cognitive impairment (VCI), and the accumulation of amyloid β-protein (Aβ) may be significantly involved in CSVD-induced VCI. The imbalance between Aβ production and clearance is believed to be an important pathological mechanism of...

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Detalles Bibliográficos
Autores principales: Liu, Xiao lu, Ouyang, Fu bing, Hu, Liu ting, Sun, Pei, Yang, Jing, Sun, Yuan jing, Liao, Meng shi, Lan, Lin fang, Pei, Zhong, Fan, Yu hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160459/
https://www.ncbi.nlm.nih.gov/pubmed/35663575
http://dx.doi.org/10.3389/fnagi.2022.883503

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