Cargando…

Machine Learning-Assisted Screening of Herbal Medicine Extracts as Vaccine Adjuvants

Adjuvants are important vaccine components, composed of a variety of chemical and biological materials that enhance the vaccine antigen-specific immune responses by stimulating the innate immune cells in both direct and indirect manners to produce a variety cytokines, chemokines, and growth factors....

Descripción completa

Detalles Bibliográficos
Autores principales:	Hioki, Kou, Hayashi, Tomoya, Natsume-Kitatani, Yayoi, Kobiyama, Kouji, Temizoz, Burcu, Negishi, Hideo, Kawakami, Hitomi, Fuchino, Hiroyuki, Kuroda, Etsushi, Coban, Cevayir, Kawahara, Nobuo, Ishii, Ken J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160479/ https://www.ncbi.nlm.nih.gov/pubmed/35663999 http://dx.doi.org/10.3389/fimmu.2022.847616

Ejemplares similares

Cyclic GMP-AMP Triggers Asthma in an IL-33-Dependent Manner That Is Blocked by Amlexanox, a TBK1 Inhibitor
por: Ozasa, Koji, et al.
Publicado: (2019)

Circulating nano-particulate TLR9 agonist scouts out tumor microenvironment to release immunogenic dead tumor cells
por: Kitahata, Yuji, et al.
Publicado: (2016)

TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN
por: Temizoz, Burcu, et al.
Publicado: (2015)

Vaccine adjuvants as potential cancer immunotherapeutics
por: Temizoz, Burcu, et al.
Publicado: (2016)

Particulate Adjuvant and Innate Immunity: Past Achievements, Present Findings, and Future Prospects
por: Kuroda, Etsushi, et al.
Publicado: (2013)

RNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, Endocine
por: Hayashi, Masayuki, et al.
Publicado: (2016)

ZBP1 governs the inflammasome-independent IL-1α and neutrophil inflammation that play a dual role in anti-influenza virus immunity
por: Momota, Masatoshi, et al.
Publicado: (2019)

The Chemotherapeutic Agent DMXAA as a Unique IRF3-Dependent Type-2 Vaccine Adjuvant
por: Tang, Choon Kit, et al.
Publicado: (2013)

DNA vaccines: A simple DNA sensing matter?
por: Coban, Cevayir, et al.
Publicado: (2013)

Innate Immune Signaling by, and Genetic Adjuvants for DNA Vaccination
por: Kobiyama, Kouji, et al.
Publicado: (2013)

Development of Nonaggregating Poly-A Tailed Immunostimulatory A/D Type CpG Oligodeoxynucleotides Applicable for Clinical Use
por: Aoshi, Taiki, et al.
Publicado: (2015)

B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
por: Lee, Michelle S.J., et al.
Publicado: (2021)

NMDA receptor‐dependent and ‐independent effects of natural compounds and crude drugs on synaptic states as revealed by drebrin imaging analysis
por: Koganezawa, Noriko, et al.
Publicado: (2021)

Toxicity of Jegosaponins A and B from Styrax japonica Siebold et al. Zuccarini in Prostate Cancer Cells and Zebrafish Embryos Resulting from Increased Membrane Permeability
por: Nishimura, Moe, et al.
Publicado: (2021)

DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination
por: Hayashi, Tomoya, et al.
Publicado: (2018)

Classification of Promoters Based on the Combination of Core Promoter Elements Exhibits Different Histone Modification Patterns
por: Natsume-Kitatani, Yayoi, et al.
Publicado: (2016)

Genome-Wide Integration on Transcription Factors, Histone Acetylation and Gene Expression Reveals Genes Co-Regulated by Histone Modification Patterns
por: Natsume-Kitatani, Yayoi, et al.
Publicado: (2011)

Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines
por: Hayashi, Masayuki, et al.
Publicado: (2016)

The host targeting effect of chloroquine in malaria
por: Coban, Cevayir
Publicado: (2020)

Tissue-specific immunopathology during malaria infection
por: Coban, Cevayir, et al.
Publicado: (2018)

DruMAP: A Novel Drug Metabolism and Pharmacokinetics Analysis Platform
por: Kawashima, Hitoshi, et al.
Publicado: (2023)

Interactive Toxicogenomics: Gene set discovery, clustering and analysis in Toxygates
por: Nyström-Persson, Johan, et al.
Publicado: (2017)

CpG ODN (K3)—toll-like receptor 9 agonist—induces Th1-type immune response and enhances cytotoxic activity in advanced lung cancer patients: a phase I study
por: Otsuka, Tomoyuki, et al.
Publicado: (2022)

Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination
por: Jounai, Nao, et al.
Publicado: (2013)

Data Curation can Improve the Prediction Accuracy of Metabolic Intrinsic Clearance
por: Esaki, Tsuyoshi, et al.
Publicado: (2018)

Panomicon: A web-based environment for interactive, visual analysis of multi-omics data
por: Allendes Osorio, Rodolfo S., et al.
Publicado: (2020)

Development of an in silico prediction system of human renal excretion and clearance from chemical structure information incorporating fraction unbound in plasma as a descriptor
por: Watanabe, Reiko, et al.
Publicado: (2019)

Mouse tissue glycome atlas 2022 highlights inter-organ variation in major N-glycan profiles
por: Otaki, Michiru, et al.
Publicado: (2022)

In Vitro Anti-Cytomegalovirus Activity of Kampo (Japanese Herbal) Medicine
por: Murayama, Tsugiya, et al.
Publicado: (2004)

IL-33 Is Essential for Adjuvant Effect of Hydroxypropyl-β-Cyclodexrin on the Protective Intranasal Influenza Vaccination
por: Kobari, Shingo, et al.
Publicado: (2020)

Role of Extrachromosomal Histone H2B on Recognition of DNA Viruses and Cell Damage
por: Kobiyama, Kouji, et al.
Publicado: (2013)

Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific
por: Nishijima, Nobuo, et al.
Publicado: (2017)

A-910823, a squalene-based emulsion adjuvant, induces T follicular helper cells and humoral immune responses via α-tocopherol component
por: Yoshioka, Yuya, et al.
Publicado: (2023)

Allergic Responses Induced by the Immunomodulatory Effects of Nanomaterials upon Skin Exposure
por: Yoshioka, Yasuo, et al.
Publicado: (2017)

Safety and Efficacy Assessment of Isoflavones from Pueraria (Kudzu) Flower Extract in Ovariectomised Mice: A Comparison with Soy Isoflavones
por: Tousen, Yuko, et al.
Publicado: (2019)

Method for preparing DNA from feces in guanidine thiocyanate solution affects 16S rRNA-based profiling of human microbiota diversity
por: Hosomi, Koji, et al.
Publicado: (2017)

Essential role of IPS-1 in innate immune responses against RNA viruses
por: Kumar, Himanshu, et al.
Publicado: (2006)

T Helper 17 Promotes Induction of Antigen-Specific Gut-Mucosal Cytotoxic T Lymphocytes following Adenovirus Vector Vaccination
por: Hemmi, Masahisa, et al.
Publicado: (2017)

Does it take three to tango? An unsuspected multimorbidity of CD8(+) T cell lymphoproliferative disorder, malaria, and EBV infection
por: Ekemen, Suheyla, et al.
Publicado: (2018)

Cinnamomum verum J. Presl Bark Contains High Contents of Nicotinamide Mononucleotide
por: Yan, Jing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_95kdeb3fchvgq9hqbmjhi33g12