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Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV)
The last 2 years have been dominated by coronavirus disease-2019 (COVID-19), its various presentations, complications, and their management. The first COVID-19 vaccine, produced by Pfizer-BioNTech, was granted regulatory approval on December 2, 2020, by the UK medicines regulator medicines and healt...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Jaypee Brothers Medical Publishers
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160620/ https://www.ncbi.nlm.nih.gov/pubmed/35719439 http://dx.doi.org/10.5005/jp-journals-10071-24214 |
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author | Ganapathiram, Ram Narayanan Hudson, Sonia |
author_facet | Ganapathiram, Ram Narayanan Hudson, Sonia |
author_sort | Ganapathiram, Ram Narayanan |
collection | PubMed |
description | The last 2 years have been dominated by coronavirus disease-2019 (COVID-19), its various presentations, complications, and their management. The first COVID-19 vaccine, produced by Pfizer-BioNTech, was granted regulatory approval on December 2, 2020, by the UK medicines regulator medicines and healthcare products regulatory agency (MHRA). It was evaluated for emergency use authorization (EUA) status by the US Food and Drug Administration (FDA) and in several other countries. Following millions of doses, during the early months of 2021, reports of side effects of the vaccines began to emerge. In this case report, we discuss the case of a 22-year-old female patient who presented with fever and confusion, with later progression to multiple organ failure, following administration of Pfizer-BioNTech vaccine. She was successfully treated with intravenous (IV) immunoglobulin (Ig) and high-dose IV corticosteroids. This case report is unique as lymph node biopsy was carried out—this showed marked suppurative inflammation with vasculitic changes, thus supporting the diagnosis. HOW TO CITE THIS ARTICLE: Ganapathiram RN, Hudson S. Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV). Indian J Crit Care Med 2022;26(5):649–650. |
format | Online Article Text |
id | pubmed-9160620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Jaypee Brothers Medical Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-91606202022-06-17 Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV) Ganapathiram, Ram Narayanan Hudson, Sonia Indian J Crit Care Med Case Report The last 2 years have been dominated by coronavirus disease-2019 (COVID-19), its various presentations, complications, and their management. The first COVID-19 vaccine, produced by Pfizer-BioNTech, was granted regulatory approval on December 2, 2020, by the UK medicines regulator medicines and healthcare products regulatory agency (MHRA). It was evaluated for emergency use authorization (EUA) status by the US Food and Drug Administration (FDA) and in several other countries. Following millions of doses, during the early months of 2021, reports of side effects of the vaccines began to emerge. In this case report, we discuss the case of a 22-year-old female patient who presented with fever and confusion, with later progression to multiple organ failure, following administration of Pfizer-BioNTech vaccine. She was successfully treated with intravenous (IV) immunoglobulin (Ig) and high-dose IV corticosteroids. This case report is unique as lymph node biopsy was carried out—this showed marked suppurative inflammation with vasculitic changes, thus supporting the diagnosis. HOW TO CITE THIS ARTICLE: Ganapathiram RN, Hudson S. Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV). Indian J Crit Care Med 2022;26(5):649–650. Jaypee Brothers Medical Publishers 2022-05 /pmc/articles/PMC9160620/ /pubmed/35719439 http://dx.doi.org/10.5005/jp-journals-10071-24214 Text en Copyright © 2022; The Author(s). https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2022 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Ganapathiram, Ram Narayanan Hudson, Sonia Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV) |
title | Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV) |
title_full | Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV) |
title_fullStr | Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV) |
title_full_unstemmed | Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV) |
title_short | Multisystem Inflammatory Syndrome in Adult Following COVID-19 Vaccination (MIS-AV) |
title_sort | multisystem inflammatory syndrome in adult following covid-19 vaccination (mis-av) |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160620/ https://www.ncbi.nlm.nih.gov/pubmed/35719439 http://dx.doi.org/10.5005/jp-journals-10071-24214 |
work_keys_str_mv | AT ganapathiramramnarayanan multisysteminflammatorysyndromeinadultfollowingcovid19vaccinationmisav AT hudsonsonia multisysteminflammatorysyndromeinadultfollowingcovid19vaccinationmisav |