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Traffic Patterns of the Migrating Endothelium: How Force Transmission Regulates Vascular Malformation and Functional Shunting During Angiogenic Remodelling

Angiogenesis occurs in distinct phases: initial spouting is followed by remodelling in which endothelial cells (ECs) composing blood vessels rearrange by migrating against the direction of flow. Abnormal remodelling can result in vascular malformation. Such is the case in mutation of the Alk1 recept...

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Detalles Bibliográficos
Autores principales: Edgar, Lowell T., Park, Hyojin, Crawshaw, Jessica R., Osborne, James M., Eichmann, Anne, Bernabeu, Miguel O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160721/
https://www.ncbi.nlm.nih.gov/pubmed/35663401
http://dx.doi.org/10.3389/fcell.2022.840066