Cargando…

Pentoxifylline Inhibits Pulmonary Fibrosis by Regulating Cellular Senescence in Mice

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease, and its occurrence and development are mediated by cellular senescence. Drugs targeting senescent cells seem like a promising and efficacious strategy for IPF treatment. Previous studies have illustrated that pentoxifylline (PTX)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Yifan, Xu, Zhihao, Zhou, Beibei, Ma, Keer, Jiang, Mengyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160723/ https://www.ncbi.nlm.nih.gov/pubmed/35662697 http://dx.doi.org/10.3389/fphar.2022.848263

Ejemplares similares

Quercetin Alleviates Pulmonary Fibrosis in Mice Exposed to Silica by Inhibiting Macrophage Senescence
por: Geng, Fei, et al.
Publicado: (2022)

Fibroblast Senescence in Idiopathic Pulmonary Fibrosis
por: Lin, Yifan, et al.
Publicado: (2020)

Cellular Senescence in Kidney Fibrosis: Pathologic Significance and Therapeutic Strategies
por: Xu, Jie, et al.
Publicado: (2020)

Yiqi Huayu decoction alleviates bleomycin-induced pulmonary fibrosis in rats by inhibiting senescence
por: Zuo, Biao, et al.
Publicado: (2022)

Senescent AECⅡ and the implication for idiopathic pulmonary fibrosis treatment
por: Zhang, Tingwei, et al.
Publicado: (2022)

Sodium Houttuyfonate Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice
por: Shen, Yun-hui, et al.
Publicado: (2021)

Cellular Senescence in Idiopathic Pulmonary Fibrosis
por: Kellogg, D. L., et al.
Publicado: (2021)

Pentoxifylline Inhibits Epidural Fibrosis in Post-Laminectomy Rats
por: Kelten, Bilal, et al.
Publicado: (2016)

Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Han, Yuanyuan, et al.
Publicado: (2021)

Perspectives of PDE inhibitor on treating idiopathic pulmonary fibrosis
por: Yang, Xudan, et al.
Publicado: (2023)

Biomarkers of cellular senescence in idiopathic pulmonary fibrosis
por: Aversa, Zaira, et al.
Publicado: (2023)

Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice
por: Li, Xiaohe, et al.
Publicado: (2021)

Tianlongkechuanling Inhibits Pulmonary Fibrosis Through Down-Regulation of Arginase-Ornithine Pathway
por: Zhang, Lili, et al.
Publicado: (2021)

Therapeutic effects of pentoxifylline on invasive pulmonary aspergillosis in immunosuppressed mice
por: Feng, Chunlai, et al.
Publicado: (2021)

Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence
por: Jiang, Yue-Hua, et al.
Publicado: (2020)

Dehydrocostus Lactone Attenuates the Senescence of Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration via Inhibition of STING-TBK1/NF-κB and MAPK Signaling
por: Chen, Zhiqian, et al.
Publicado: (2021)

Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence
por: Zhang, Li, et al.
Publicado: (2020)

Editorial: Premature Aging and Senescence in Renal Fibrosis
por: Samarakoon, Rohan, et al.
Publicado: (2021)

Protective Effect of Arbidol Against Pulmonary Fibrosis and Sepsis in Mice
por: Li, Hailong, et al.
Publicado: (2021)

The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice
por: Yu, Yanzhen, et al.
Publicado: (2021)

Antifibrotic Mechanism of Cinobufagin in Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Li, Xiaohe, et al.
Publicado: (2019)

Corrigendum: Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence
por: Jiang, Yue-Hua, et al.
Publicado: (2020)

Advances in cellular senescence in idiopathic pulmonary fibrosis (Review)
por: Han, Shan, et al.
Publicado: (2023)

Cellular Senescence: A Troy Horse in Pulmonary Fibrosis
por: Wan, Ruyan, et al.
Publicado: (2023)

Treatment of Poor Sperm Quality and Erectile Dysfunction With Oral Pentoxifylline: A Systematic Review
por: Lu, Yi, et al.
Publicado: (2022)

Cellular Senescence and the Kidney: Potential Therapeutic Targets and Tools
por: Knoppert, Sebastian N., et al.
Publicado: (2019)

High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis
por: Maique, Jenny, et al.
Publicado: (2020)

Nitidine Chloride Alleviates Inflammation and Cellular Senescence in Murine Osteoarthritis Through Scavenging ROS
por: Lin, Changjian, et al.
Publicado: (2022)

Comprehensive analysis for cellular senescence-related immunogenic characteristics and immunotherapy prediction of acute myeloid leukemia
por: Mao, Yan, et al.
Publicado: (2022)

Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice
por: Huang, Jizhen, et al.
Publicado: (2020)

Antifibrotic Mechanism of Piceatannol in Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Sheng, Hanjing, et al.
Publicado: (2022)

Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Inhibiting Ferroptosis Signaling Pathway
por: Yuan, Leyong, et al.
Publicado: (2022)

Cellular Mechanisms of Liver Fibrosis
por: Acharya, Pragyan, et al.
Publicado: (2021)

Cellular Senescence and Senotherapies in the Kidney: Current Evidence and Future Directions
por: Docherty, Marie Helena, et al.
Publicado: (2020)

GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition
por: Zhou, Xiao-Ming, et al.
Publicado: (2017)

Bone morphogenetic protein 4 inhibits pulmonary fibrosis by modulating cellular senescence and mitophagy in lung fibroblasts
por: Guan, Ruijuan, et al.
Publicado: (2022)

Non-coding RNAs as Regulators of Cellular Senescence in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease
por: Omote, Norihito, et al.
Publicado: (2020)

Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway
por: Li, Xiaohe, et al.
Publicado: (2021)

Diverse Roles of Cellular Senescence in Skeletal Muscle Inflammation, Regeneration, and Therapeutics
por: Saito, Yuki, et al.
Publicado: (2021)

Cellular Senescence in Lung Fibrosis
por: Hernandez-Gonzalez, Fernanda, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hn7p8lrfkpttidm1133c33ikut