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Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis
OBJECTIVES: The aim of this investigation was to evaluate the effectiveness of collagen cross-linking agents (CCLAs) used in combination with the adhesive technique in restorative procedures. MATERIALS AND METHODS: In this systematic review, the authors followed the Preferred Reporting Items for Sys...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Conservative Dentistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160760/ https://www.ncbi.nlm.nih.gov/pubmed/35692222 http://dx.doi.org/10.5395/rde.2022.47.e23 |
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author | Silva, Julianne Coelho Cetira Filho, Edson Luiz Silva, Paulo Goberlânio de Barros Costa, Fábio Wildson Gurgel Saboia, Vicente de Paulo Aragão |
author_facet | Silva, Julianne Coelho Cetira Filho, Edson Luiz Silva, Paulo Goberlânio de Barros Costa, Fábio Wildson Gurgel Saboia, Vicente de Paulo Aragão |
author_sort | Silva, Julianne Coelho |
collection | PubMed |
description | OBJECTIVES: The aim of this investigation was to evaluate the effectiveness of collagen cross-linking agents (CCLAs) used in combination with the adhesive technique in restorative procedures. MATERIALS AND METHODS: In this systematic review, the authors followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. An electronic search was performed using PubMed, Scopus, Web of Science, Cochrane Library, LILACS, and DOSS, up to October 2020. The gray literature was also researched. Only randomized clinical trials were selected. RESULTS: The selection process yielded 3 studies from the 838 retrieved. The addition of CCLAs in the retention of restorations increased the number of events. The postoperative sensitivity scores and marginal adaptation scores showed no significant difference between the CCLA and control groups, and the marginal pigmentation scores showed a significant increase in the CCLA group. There were no caries events in any group throughout the evaluation period. CONCLUSIONS: This systematic review showed that there is no clinical efficacy to justify the use of CCLAs in the protocols performed. |
format | Online Article Text |
id | pubmed-9160760 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Korean Academy of Conservative Dentistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-91607602022-06-10 Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis Silva, Julianne Coelho Cetira Filho, Edson Luiz Silva, Paulo Goberlânio de Barros Costa, Fábio Wildson Gurgel Saboia, Vicente de Paulo Aragão Restor Dent Endod Research Article OBJECTIVES: The aim of this investigation was to evaluate the effectiveness of collagen cross-linking agents (CCLAs) used in combination with the adhesive technique in restorative procedures. MATERIALS AND METHODS: In this systematic review, the authors followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. An electronic search was performed using PubMed, Scopus, Web of Science, Cochrane Library, LILACS, and DOSS, up to October 2020. The gray literature was also researched. Only randomized clinical trials were selected. RESULTS: The selection process yielded 3 studies from the 838 retrieved. The addition of CCLAs in the retention of restorations increased the number of events. The postoperative sensitivity scores and marginal adaptation scores showed no significant difference between the CCLA and control groups, and the marginal pigmentation scores showed a significant increase in the CCLA group. There were no caries events in any group throughout the evaluation period. CONCLUSIONS: This systematic review showed that there is no clinical efficacy to justify the use of CCLAs in the protocols performed. The Korean Academy of Conservative Dentistry 2022-05-06 /pmc/articles/PMC9160760/ /pubmed/35692222 http://dx.doi.org/10.5395/rde.2022.47.e23 Text en Copyright © 2022. The Korean Academy of Conservative Dentistry https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Silva, Julianne Coelho Cetira Filho, Edson Luiz Silva, Paulo Goberlânio de Barros Costa, Fábio Wildson Gurgel Saboia, Vicente de Paulo Aragão Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis |
title | Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis |
title_full | Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis |
title_fullStr | Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis |
title_full_unstemmed | Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis |
title_short | Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis |
title_sort | is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? a systematic review and meta-analysis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160760/ https://www.ncbi.nlm.nih.gov/pubmed/35692222 http://dx.doi.org/10.5395/rde.2022.47.e23 |
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