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Mitochondrial Cytochrome c Oxidase Defects Alter Cellular Homeostasis of Transition Metals

The redox activity of cytochrome c oxidase (COX), the terminal oxidase of the mitochondrial respiratory chain (MRC), depends on the incorporation of iron and copper into its catalytic centers. Many mitochondrial proteins have specific roles for the synthesis and delivery of metal-containing cofactor...

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Detalles Bibliográficos
Autores principales:	Brischigliaro, Michele, Badocco, Denis, Costa, Rodolfo, Viscomi, Carlo, Zeviani, Massimo, Pastore, Paolo, Fernández-Vizarra, Erika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160823/ https://www.ncbi.nlm.nih.gov/pubmed/35663391 http://dx.doi.org/10.3389/fcell.2022.892069

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