Constitutive expression of the global regulator AbrB restores the growth defect of a genome-reduced Bacillus subtilis strain and improves its metabolite production

Partial bacterial genome reduction by genome engineering can improve the productivity of various metabolites, possibly via deletion of non-essential genome regions involved in undesirable metabolic pathways competing with pathways for the desired end products. However, such reduction may cause growt...

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Detalles Bibliográficos
Autores principales: Yamamoto, Junya, Chumsakul, Onuma, Toya, Yoshihiro, Morimoto, Takuya, Liu, Shenghao, Masuda, Kenta, Kageyama, Yasushi, Hirasawa, Takashi, Matsuda, Fumio, Ogasawara, Naotake, Shimizu, Hiroshi, Yoshida, Ken-ichi, Oshima, Taku, Ishikawa, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160880/
https://www.ncbi.nlm.nih.gov/pubmed/35608323
http://dx.doi.org/10.1093/dnares/dsac015

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