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Clinical Significance of Gene Mutations and Polymorphic Variants and their Association with Prostate Cancer Risk in Polish Men

Objectives: We tested the association of germline variants in BRCA1, BRCA2, CHEK2, CDKN2A, CYP1B1, HOXB13, MLH1, NBS1, NOD2 and PALB2 genes, as well as in 8q24 region, with prostate cancer (PC) risk and estimated their impact on disease clinical course, including overall survival time in Polish men...

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Detalles Bibliográficos
Autores principales: Heise, Marta, Jarzemski, Piotr, Nowak, Dagmara, Bąk, Aneta, Junkiert-Czarnecka, Anna, Pilarska-Deltow, Maria, Borysiak, Maciej, Pilarska, Beata, Haus, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160909/
https://www.ncbi.nlm.nih.gov/pubmed/35638715
http://dx.doi.org/10.1177/10732748211062342