Cargando…

1-O-Actylbritannilactone Ameliorates Alcohol-Induced Hepatotoxicity through Regulation of ROS/Akt/NF-κB-Mediated Apoptosis and Inflammation

[Image: see text] 1-O-Acetylbritannilactone (ABL) is a marker component of Inula britannica L. and is reported to exhibit multiple pharmacological activities, including antiaging, anti-inflammatory, and antidiabetic properties. Although the protective effect of Inula britannica L. on animal models o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Li-ya, Yang, Zhen, Wang, Ying, Hu, Jun-nan, Lu, Ya-wei, Zhang, Hao, Jiang, Shuang, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161245/ https://www.ncbi.nlm.nih.gov/pubmed/35664604 http://dx.doi.org/10.1021/acsomega.2c01681

Ejemplares similares

Maltol Improves APAP-Induced Hepatotoxicity by Inhibiting Oxidative Stress and Inflammation Response via NF-κB and PI3K/Akt Signal Pathways
por: Wang, Zi, et al.
Publicado: (2019)

Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF-κB signaling pathways
por: Wu, Dongdong, et al.
Publicado: (2017)

Platycodon grandiflorum Saponins Ameliorate Cisplatin-Induced Acute Nephrotoxicity through the NF-κB-Mediated Inflammation and PI3K/Akt/Apoptosis Signaling Pathways
por: Zhang, Weizhe, et al.
Publicado: (2018)

Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways
por: Zhang, Guo-Yu, et al.
Publicado: (2018)

Ginsenoside Rk1 ameliorates paracetamol-induced hepatotoxicity in mice through inhibition of inflammation, oxidative stress, nitrative stress and apoptosis
por: Hu, Jun-Nan, et al.
Publicado: (2019)

Osteogenic protein-1 inhibits nucleus pulposus cell apoptosis through regulating the NF-κB/ROS pathway in an inflammation environment
por: Yu, Wei, et al.
Publicado: (2018)

Hesperidin ameliorates cisplatin induced hepatotoxicity and attenuates oxidative damage, cell apoptosis, and inflammation in rats
por: Aboraya, Dina M., et al.
Publicado: (2022)

Quinalizarin induces ROS-mediated apoptosis via the MAPK, STAT3 and NF-κB signaling pathways in human breast cancer cells
por: Zang, Yan-Qing, et al.
Publicado: (2019)

Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway
por: Gupta, Subash C., et al.
Publicado: (2014)

Fingolimod ameliorates chronic experimental autoimmune neuritis by modulating inflammatory cytokines and Akt/mTOR/NF‐κB signaling
por: Feng, Yuan, et al.
Publicado: (2023)

Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity
por: Kyritsi, Konstantina, et al.
Publicado: (2023)

Subanesthetic Isoflurane Reduces Zymosan-Induced Inflammation in Murine Kupffer Cells by Inhibiting ROS-Activated p38 MAPK/NF-κB Signaling
por: Wang, Hui, et al.
Publicado: (2014)

Sodium fluoride induces apoptosis in mouse splenocytes by activating ROS-dependent NF-κB signaling
por: Deng, Huidan, et al.
Publicado: (2017)

Neferine ameliorates cardiomyoblast apoptosis induced by doxorubicin: possible role in modulating NADPH oxidase/ROS-mediated NFκB redox signaling cascade
por: Priya, Lohanathan Bharathi, et al.
Publicado: (2017)

The Elk-3 target Abhd10 ameliorates hepatotoxic injury and fibrosis in alcoholic liver disease
por: Li, Tian-Zhu, et al.
Publicado: (2023)

Oridonin stabilizes retinoic acid receptor alpha through ROS-activated NF-κB signaling
por: Cao, Yang, et al.
Publicado: (2015)

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy
por: Yi, Hong, et al.
Publicado: (2017)

Kweichow Moutai ameliorates alcohol‐induced liver fibrosis in mice by targeting the NFκB pathway
por: Yang, Tao, et al.
Publicado: (2020)

Zeaxanthin Induces Apoptosis via ROS-Regulated MAPK and AKT Signaling Pathway in Human Gastric Cancer Cells
por: Sheng, Ya-Nan, et al.
Publicado: (2020)

TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NF-κB pathway
por: Huang, Ji-Cheng, et al.
Publicado: (2022)

Kinetin Ameliorates Cisplatin-Induced Hepatotoxicity and Lymphotoxicity via Attenuating Oxidative Damage, Cell Apoptosis and Inflammation in Rats
por: Fathy, Moustafa, et al.
Publicado: (2022)

Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation
por: Peng, Shuang, et al.
Publicado: (2016)

Calycosin Induces Gastric Cancer Cell Apoptosis via the ROS-Mediated MAPK/STAT3/NF-κB Pathway
por: Zhang, Yu, et al.
Publicado: (2021)

Upregulation of Akt/NF-κB-regulated inflammation and Akt/Bad-related apoptosis signaling pathway involved in hepatic carcinoma process: suppression by carnosic acid nanoparticle
por: Tang, Bo, et al.
Publicado: (2016)

Fusobacterium nucleatum Facilitates Apoptosis, ROS Generation, and Inflammatory Cytokine Production by Activating AKT/MAPK and NF-κB Signaling Pathways in Human Gingival Fibroblasts
por: Kang, Wenyan, et al.
Publicado: (2019)

Curcumin Ameliorates Lead-Induced Hepatotoxicity by Suppressing Oxidative Stress and Inflammation, and Modulating Akt/GSK-3β Signaling Pathway
por: Alhusaini, Ahlam, et al.
Publicado: (2019)

Kaempferol ameliorates Cisplatin induced nephrotoxicity by modulating oxidative stress, inflammation and apoptosis via ERK and NF-κB pathways
por: Wang, Zhu, et al.
Publicado: (2020)

Cimifugin ameliorates imiquimod-induced psoriasis by inhibiting oxidative stress and inflammation via NF-κB/MAPK pathway
por: Liu, Aimin, et al.
Publicado: (2020)

Juglanthraquinone C Induces Intracellular ROS Increase and Apoptosis by Activating the Akt/Foxo Signal Pathway in HCC Cells
por: Hou, Ya-Qin, et al.
Publicado: (2016)

Qizhi Kebitong Formula Ameliorates Streptozocin-Induced Diabetic Osteoporosis through Regulating the PI3K/Akt/NF-κB Pathway
por: Tian, Lulu, et al.
Publicado: (2022)

Bestrophin 3 Ameliorates TNFα-Induced Inflammation by Inhibiting NF-κB Activation in Endothelial Cells
por: Song, Wei, et al.
Publicado: (2014)

Diacerein ameliorates acetaminophen hepatotoxicity in rats via inhibiting HMGB1/TLR4/NF-κB and upregulating PPAR-γ signal
por: Mohamed Kamel, Gellan Alaa, et al.
Publicado: (2022)

PLCA8 suppresses breast cancer apoptosis by activating the PI3k/AKT/NF‐κB pathway
por: Mao, Misha, et al.
Publicado: (2019)

Oxalate-induced apoptosis through ERS-ROS–NF-κB signalling pathway in renal tubular epithelial cell
por: Ming, Shaoxiong, et al.
Publicado: (2022)

Zerumbone ameliorates the inflammatory response and organ damage in severe acute pancreatitis via the ROS/NF-κB pathway
por: Zhang, Fengmei, et al.
Publicado: (2023)

Cyanidin ameliorates cisplatin-induced cardiotoxicity via inhibition of ROS-mediated apoptosis
por: Qian, Peng, et al.
Publicado: (2018)

Oxymatrine Prevents NF-κB Nuclear Translocation And Ameliorates Acute Intestinal Inflammation
por: Guzman, Javier Rivera, et al.
Publicado: (2013)

Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
por: Lee, Wonhwa, et al.
Publicado: (2020)

Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-κB axis and ameliorates osteoarthritis in mice
por: Zhang, Peng, et al.
Publicado: (2023)

Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF-κB Axis
por: Han, Chenglin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5jrctpbk9ngq0t7l7bh3i8e5s3