SARS-CoV-2 Within-Host and in vitro Genomic Variability and Sub-Genomic RNA Levels Indicate Differences in Viral Expression Between Clinical Cohorts and in vitro Culture

BACKGROUND: Low frequency intrahost single nucleotide variants (iSNVs) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) have been increasingly recognised as predictive indicators of positive selection. Particularly as growing numbers of SARS-CoV-2 variants of interest (VOI) and concer...

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Detalles Bibliográficos
Autores principales: Agius, Jessica E., Johnson-Mackinnon, Jessica C., Fong, Winkie, Gall, Mailie, Lam, Connie, Basile, Kerri, Kok, Jen, Arnott, Alicia, Sintchenko, Vitali, Rockett, Rebecca J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161297/
https://www.ncbi.nlm.nih.gov/pubmed/35663867
http://dx.doi.org/10.3389/fmicb.2022.824217

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