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High cyclin E1 protein, but not gene amplification, is prognostic for basal‐like breast cancer

Basal‐like breast cancer (BLBC) has a greater overlap in molecular features with high‐grade serous ovarian cancer (HGSOC) than with other breast cancer subtypes. Similarities include BRCA1 mutation, high frequency of TP53 mutation, and amplification of CCNE1 (encoding the cyclin E1 protein) in 6–34%...

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Detalles Bibliográficos
Autores principales: Aziz, Diar, Lee, Christine, Chin, Venessa, Fernandez, Kristine J, Phan, Zoe, Waring, Paul, Caldon, C Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161326/
https://www.ncbi.nlm.nih.gov/pubmed/35384378
http://dx.doi.org/10.1002/cjp2.269

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