Twin peaks: The Omicron SARS-CoV-2 BA.1 and BA.2 epidemics in England

Rapid transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has led to record-breaking incidence rates around the world. The REal-time Assessment of Community Transmission-1 (REACT-1) study has tracked SARS-CoV-2 infection in England using reverse transcription...

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Detalles Bibliográficos
Autores principales: Elliott, Paul, Eales, Oliver, Steyn, Nicholas, Tang, David, Bodinier, Barbara, Wang, Haowei, Elliott, Joshua, Whitaker, Matthew, Atchison, Christina, Diggle, Peter J., Page, Andrew J., Trotter, Alexander J., Ashby, Deborah, Barclay, Wendy, Taylor, Graham, Ward, Helen, Darzi, Ara, Cooke, Graham S., Donnelly, Christl A., Chadeau-Hyam, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161371/
https://www.ncbi.nlm.nih.gov/pubmed/35608440
http://dx.doi.org/10.1126/science.abq4411
Descripción
Sumario:Rapid transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has led to record-breaking incidence rates around the world. The REal-time Assessment of Community Transmission-1 (REACT-1) study has tracked SARS-CoV-2 infection in England using reverse transcription polymerase chain reaction (RT-PCR) results from self-administered throat and nose swabs from randomly selected participants aged 5+ years, approximately monthly from May 2020 to March 2022. Weighted prevalence in March 2022 was the highest recorded in REACT-1 at 6.37% (N=109,181) with Omicron BA.2 largely replacing BA.1. Prevalence was increasing overall with the greatest increase in those aged 65-74 and 75+ years. This was associated with increased hospitalizations and deaths but at much lower levels than in previous waves against a backdrop of high levels of vaccination.

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