Toward Light-Controlled Supramolecular Peptide Dimerization

[Image: see text] The selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor–ligand complex with cucurbit[8]uril into a homoternary FGG(2)@CB8 assembly. The resulting light-induced dimerization of the model peptide provides a tool for the implem...

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Detalles Bibliográficos
Autores principales: Fernandes, Rita J., Remón, Patricia, Moro, Artur J., Seco, André, Ferreira, Ana S. D., Pischel, Uwe, Basílio, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161448/
https://www.ncbi.nlm.nih.gov/pubmed/34060851
http://dx.doi.org/10.1021/acs.joc.1c00464
Descripción
Sumario:[Image: see text] The selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor–ligand complex with cucurbit[8]uril into a homoternary FGG(2)@CB8 assembly. The resulting light-induced dimerization of the model peptide provides a tool for the implementation of stimuli-responsive supramolecular chemistry in biologically relevant contexts.

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