Toward Light-Controlled Supramolecular Peptide Dimerization

[Image: see text] The selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor–ligand complex with cucurbit[8]uril into a homoternary FGG(2)@CB8 assembly. The resulting light-induced dimerization of the model peptide provides a tool for the implem...

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Autores principales: Fernandes, Rita J., Remón, Patricia, Moro, Artur J., Seco, André, Ferreira, Ana S. D., Pischel, Uwe, Basílio, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161448/
https://www.ncbi.nlm.nih.gov/pubmed/34060851
http://dx.doi.org/10.1021/acs.joc.1c00464
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author Fernandes, Rita J.
Remón, Patricia
Moro, Artur J.
Seco, André
Ferreira, Ana S. D.
Pischel, Uwe
Basílio, Nuno
author_facet Fernandes, Rita J.
Remón, Patricia
Moro, Artur J.
Seco, André
Ferreira, Ana S. D.
Pischel, Uwe
Basílio, Nuno
author_sort Fernandes, Rita J.
collection PubMed
description [Image: see text] The selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor–ligand complex with cucurbit[8]uril into a homoternary FGG(2)@CB8 assembly. The resulting light-induced dimerization of the model peptide provides a tool for the implementation of stimuli-responsive supramolecular chemistry in biologically relevant contexts.
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spelling pubmed-91614482022-06-03 Toward Light-Controlled Supramolecular Peptide Dimerization Fernandes, Rita J. Remón, Patricia Moro, Artur J. Seco, André Ferreira, Ana S. D. Pischel, Uwe Basílio, Nuno J Org Chem [Image: see text] The selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor–ligand complex with cucurbit[8]uril into a homoternary FGG(2)@CB8 assembly. The resulting light-induced dimerization of the model peptide provides a tool for the implementation of stimuli-responsive supramolecular chemistry in biologically relevant contexts. American Chemical Society 2021-06-01 2021-06-18 /pmc/articles/PMC9161448/ /pubmed/34060851 http://dx.doi.org/10.1021/acs.joc.1c00464 Text en © 2021 American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Fernandes, Rita J.
Remón, Patricia
Moro, Artur J.
Seco, André
Ferreira, Ana S. D.
Pischel, Uwe
Basílio, Nuno
Toward Light-Controlled Supramolecular Peptide Dimerization
title Toward Light-Controlled Supramolecular Peptide Dimerization
title_full Toward Light-Controlled Supramolecular Peptide Dimerization
title_fullStr Toward Light-Controlled Supramolecular Peptide Dimerization
title_full_unstemmed Toward Light-Controlled Supramolecular Peptide Dimerization
title_short Toward Light-Controlled Supramolecular Peptide Dimerization
title_sort toward light-controlled supramolecular peptide dimerization
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161448/
https://www.ncbi.nlm.nih.gov/pubmed/34060851
http://dx.doi.org/10.1021/acs.joc.1c00464
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