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FUT8-Directed Core Fucosylation of N-glycans Is Regulated by the Glycan Structure and Protein Environment

[Image: see text] FUT8 is an essential α-1,6-fucosyltransferase that fucosylates the innermost GlcNAc of N-glycans, a process called core fucosylation. In vitro, FUT8 exhibits substrate preference for the biantennary complex N-glycan oligosaccharide (G0), but the role of the underlying protein/pepti...

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Detalles Bibliográficos
Autores principales:	García-García, Ana, Serna, Sonia, Yang, Zhang, Delso, Ignacio, Taleb, Víctor, Hicks, Thomas, Artschwager, Raik, Vakhrushev, Sergey Y., Clausen, Henrik, Angulo, Jesús, Corzana, Francisco, Reichardt, Niels C., Hurtado-Guerrero, Ramon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161449/ https://www.ncbi.nlm.nih.gov/pubmed/35662980 http://dx.doi.org/10.1021/acscatal.1c01698

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