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IL-39 promotes chronic graft-versus-host disease by increasing T and B Cell pathogenicity

BACKGROUND: Chronic graft-versus-host disease (cGVHD) remains a major complication during the late phase of allogeneic hematopoietic stem cell transplantation (allo-HSCT). IL-39, a newly described pro-inflammatory cytokine belonging to the IL-12 family, plays a role in lupus development. Recently, I...

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Detalles Bibliográficos
Autores principales: Lv, Kangkang, Hu, Bo, Xu, Mingzhu, Wan, Li, Jin, Ziqi, Xu, Mimi, Du, Yuanyuan, Ma, Kunpeng, Lv, Quansheng, Xu, Yang, Lei, Lei, Gong, Huanle, Liu, Haiyan, Wu, Depei, Liu, Yuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161463/
https://www.ncbi.nlm.nih.gov/pubmed/35655245
http://dx.doi.org/10.1186/s40164-022-00286-x

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