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circPDE5A regulates prostate cancer metastasis via controlling WTAP-dependent N6-methyladenisine methylation of EIF3C mRNA

BACKGROUND: Circular RNA (circRNA) is a novel class noncoding RNA (ncRNA) that plays a critical role in various cancers, including prostate cancer (PCa). However, the clinical significance, biological function, and molecular mechanisms of circRNAs in prostate cancer remain to be elucidated. METHODS:...

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Detalles Bibliográficos
Autores principales: Ding, Lifeng, Wang, Ruyue, Zheng, Qiming, Shen, Danyang, Wang, Huan, Lu, Zeyi, Luo, Wenqin, Xie, Haiyun, Ren, Liangliang, Jiang, Minxiao, Yu, Chenhao, Zhou, Zhenwei, Lin, Yudong, Lu, Haohua, Xue, Dingwei, Su, Wenjing, Xia, Liqun, Neuhaus, Jochen, Cheng, Sheng, Li, Gonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161465/
https://www.ncbi.nlm.nih.gov/pubmed/35650605
http://dx.doi.org/10.1186/s13046-022-02391-5

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