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Identification and characterization of a heme exporter from the MRP family in Drosophila melanogaster

BACKGROUND: The heme group constitutes a major functional form of iron, which plays vital roles in various biological processes including oxygen transport and mitochondrial respiration. Heme is an essential nutrient, but its pro-oxidant nature may have toxic cellular effects if present at high level...

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Detalles Bibliográficos
Autores principales: Wang, Zhiqing, Zeng, Peng, Zhou, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161523/
https://www.ncbi.nlm.nih.gov/pubmed/35655259
http://dx.doi.org/10.1186/s12915-022-01332-0