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Potent anti-tumor activity of CD45RA-targeting Hm3A4-Ranpirnase against myeloid lineage leukemias

CD45RA is a specific marker for leukemia stem cell (LSC) sub-populations in acute myeloid leukemia (AML). Ranpirnase (Rap), an amphibian RNase, has been extensively investigated in preclinical and clinical studies for its antitumor activity. Rap could be administered repeatedly to patients without i...

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Detalles Bibliográficos
Autores principales:	Li, Sisi, Wang, Zhujun, Guo, Xiaoping, Chen, Ping, Tang, Yongmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161826/ https://www.ncbi.nlm.nih.gov/pubmed/35322728 http://dx.doi.org/10.1080/21655979.2022.2054159

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