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Kukoamine A attenuates lipopolysaccharide-induced apoptosis, extracellular matrix degradation, and inflammation in nucleus pulposus cells by activating the P13K/Akt pathway

Intervertebral disc degeneration (IDD) is the leading cause of back, neck, and radicular pain. This study aims to look at the roles of Kukoamine A (KuA) in nucleus pulposus cells (NPCs) of IDD and its related potential mechanisms. Cell viability of NPCs in the control, lipopolysaccharide (LPS) and L...

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Detalles Bibliográficos
Autores principales:	Wang, Dan, Qu, Hao, Kang, Hui, Xu, Feng, Huang, Wei, Cai, Xianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161835/ https://www.ncbi.nlm.nih.gov/pubmed/35333664 http://dx.doi.org/10.1080/21655979.2022.2051855

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