The crystallin alpha B (HSPB5)-tripartite motif containing 33 (TRIM33) axis mediates myocardial fibrosis induced by angiotensinogen II through transforming growth factor-β (TGF-β1)-Smad3/4 signaling

Myocardial fibrosis, a common pathological manifestation of cardiac remodeling (CR), often leads to heart failure (HF) and even death. The underlying molecular mechanism of the role of TRIM33 in Ang II–induced myocardial fibrosis is not fully understood. We found that TRIM33 was specifically upregul...

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Detalles Bibliográficos
Autores principales: Wei, Tianwen, Du, Yingqiang, Shan, Tiankai, Chen, Jiawen, Shi, Dongwei, Yang, Tongtong, Wang, Jiankang, Zhang, Jun, Li, Yafei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161881/
https://www.ncbi.nlm.nih.gov/pubmed/35333698
http://dx.doi.org/10.1080/21655979.2022.2054913

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