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Dexmedetomidine prevents cardiomyocytes from hypoxia/reoxygenation injury via modulating tetmethylcytosine dioxygenase 1-mediated DNA demethylation of Sirtuin1

Myocardial hypoxia/reoxygenation (H/R) injury is a common pathological change in patients with acute myocardial infarction undergoing reperfusion therapy. Dexmedetomidine (DEX) has been found to substantially improve ischemia-mediated cell damage. Here, we focus on probing the role and mechanism of...

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Detalles Bibliográficos
Autores principales:	Wang, Li, Wang, Shaowei, Jia, Tong, Sun, Xiaojia, Xing, Zhen, Liu, Hui, Yao, Jie, Chen, Yanlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161963/ https://www.ncbi.nlm.nih.gov/pubmed/35387565 http://dx.doi.org/10.1080/21655979.2022.2054762

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