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Discoidin domain receptor 1a (DDR1a) confers 5-fluorouracil cytotoxicity in LoVo cell via PI3K/AKT/Bcl-2 pathway

5-Fluorouracil (5-FU) is a common chemotherapy drug for patients with advanced colorectal cancer; however, many patients develop resistance to 5-FU and suffer from treatment failure. Discoidin domain receptor 1 (DDR1) is upregulated in multiple cancers and positively associated with chemoresistance....

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Detalles Bibliográficos
Autores principales:	Xiong, Bin, Song, Fei-Xue, Chen, Hui-Ling, Wang, Xiao-Juan, Jin, Zheng-Xu, Han, Ti-Yun, Li, Yi, Zhang, De-Kui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161994/ https://www.ncbi.nlm.nih.gov/pubmed/35416117 http://dx.doi.org/10.1080/21655979.2022.2060782

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