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Omicron BA.1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes

Omicron is the evolutionarily most distinct SARS-CoV-2 variant of concern (VOC) to date. We report that Omicron BA.1 breakthrough infection in BNT162b2-vaccinated individuals resulted in strong neutralizing activity against Omicron BA.1, BA.2 and previous SARS-CoV-2 VOCs, but not against the Omicron...

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Detalles Bibliográficos
Autores principales: Quandt, Jasmin, Muik, Alexander, Salisch, Nadine, Lui, Bonny Gaby, Lutz, Sebastian, Krüger, Kimberly, Wallisch, Ann-Kathrin, Adams-Quack, Petra, Bacher, Maren, Finlayson, Andrew, Ozhelvaci, Orkun, Vogler, Isabel, Grikscheit, Katharina, Hoehl, Sebastian, Goetsch, Udo, Ciesek, Sandra, Türeci, Özlem, Sahin, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162083/
https://www.ncbi.nlm.nih.gov/pubmed/35653438
http://dx.doi.org/10.1126/sciimmunol.abq2427

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