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Dapagliflozin Attenuates Contrast-induced Acute Kidney Injury by Regulating the HIF-1α/HE4/NF-κB Pathway

Contrast-induced acute kidney injury (CI-AKI) causes clinically acquired nephropathy in patients who undergo coronary interventions. Hypoxic injury to proximal tubular epithelial cells is a pathological mechanism of CI-AKI. Previous studies have shown that hypoxia activates HIF-1α/HE4/NF-κB to enhan...

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Detalles Bibliográficos
Autores principales:	Huang, Xu, Guo, Xiaoxu, Yan, Gaoliang, Zhang, Yang, Yao, Yuyu, Qiao, Yong, Wang, Dong, Chen, Gecai, Zhang, Weiwei, Tang, Chengchun, Cao, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Journal of Cardiovascular Pharmacology 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162274/ https://www.ncbi.nlm.nih.gov/pubmed/35383661 http://dx.doi.org/10.1097/FJC.0000000000001268

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