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A new test suggests hundreds of amino acid polymorphisms in humans are subject to balancing selection
The role that balancing selection plays in the maintenance of genetic diversity remains unresolved. Here, we introduce a new test, based on the McDonald–Kreitman test, in which the number of polymorphisms that are shared between populations is contrasted to those that are private at selected and neu...
Autores principales: | Soni, Vivak, Vos, Michiel, Eyre-Walker, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162324/ https://www.ncbi.nlm.nih.gov/pubmed/35653351 http://dx.doi.org/10.1371/journal.pbio.3001645 |
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