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Resveratrol-nitric oxide donor hybrid effect on priapism in sickle cell and nitric oxide-deficient mouse

BACKGROUND: Children and adult with sickle cell disease (SCD) display priapism associated with low nitric oxide (NO) bioavailability and oxidative stress in penis. AIM: This study aimed to evaluate the effects of hybrid compound RVT-FxMe, derived from resveratrol bearing a NO-donor subunit, on two m...

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Detalles Bibliográficos
Autores principales: Pinheiro, Andressa Kely, Pereira, Dalila Andrade, dos Santos, Jean Leandro, Calmasini, Fabiano Beraldi, Alexandre, Eduardo Costa, Reis, Leonardo Oliveira, Burnett, Arthur L., Costa, Fernando Ferreira, Silva, Fábio Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162357/
https://www.ncbi.nlm.nih.gov/pubmed/35653352
http://dx.doi.org/10.1371/journal.pone.0269310