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Resveratrol-nitric oxide donor hybrid effect on priapism in sickle cell and nitric oxide-deficient mouse
BACKGROUND: Children and adult with sickle cell disease (SCD) display priapism associated with low nitric oxide (NO) bioavailability and oxidative stress in penis. AIM: This study aimed to evaluate the effects of hybrid compound RVT-FxMe, derived from resveratrol bearing a NO-donor subunit, on two m...
Autores principales: | Pinheiro, Andressa Kely, Pereira, Dalila Andrade, dos Santos, Jean Leandro, Calmasini, Fabiano Beraldi, Alexandre, Eduardo Costa, Reis, Leonardo Oliveira, Burnett, Arthur L., Costa, Fernando Ferreira, Silva, Fábio Henrique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162357/ https://www.ncbi.nlm.nih.gov/pubmed/35653352 http://dx.doi.org/10.1371/journal.pone.0269310 |
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