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The extant immunoglobulin superfamily, member 1 gene results from an ancestral gene duplication in eutherian mammals
Immunoglobulin superfamily, member 1 (IGSF1) is a transmembrane glycoprotein with high expression in the mammalian pituitary gland. Mutations in the IGSF1 gene cause congenital central hypothyroidism in humans. The IGSF1 protein is co-translationally cleaved into N- and C-terminal domains (NTD and C...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162367/ https://www.ncbi.nlm.nih.gov/pubmed/35653309 http://dx.doi.org/10.1371/journal.pone.0267744 |