Dexmedetomidine Leads to the Mitigation of Myocardial Ischemia/Reperfusion-Induced Acute Lung Injury in Diabetic Rats Via Modulation of Hypoxia-Inducible Factor-1α

INTRODUCTION: The objective of this study is to investigate the protective mechanism of dexmedetomidine (Dex) in myocardial ischemia/reperfusion (MIR)-induced acute lung injury (ALI) of diabetic rats by inhibiting hypoxia-inducible factor-1α (HIF-1α). METHODS: Initially, healthy male Sprague Dawley...

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Detalles Bibliográficos
Autores principales: Chen, Siyu, Wu, Jianjiang, Yang, Long, Tailaiti, Taiwangu, Zou, Tiantian, Huan, Yidan, Wang, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162414/
https://www.ncbi.nlm.nih.gov/pubmed/35605218
http://dx.doi.org/10.21470/1678-9741-2020-0591

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