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Organ-on-a-chip: current gaps and future directions
As an emerging hot topic of the last decade, Organ on Chip (OoC) is a new technology that is attracting interest from both basic and translational scientists. The Biochemical Society, with its mission of supporting the advancement of science, with addressing grand challenges that have societal impac...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162452/ https://www.ncbi.nlm.nih.gov/pubmed/35437569 http://dx.doi.org/10.1042/BST20200661 |
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author | Candarlioglu, Pelin L. Dal Negro, Gianni Hughes, David Balkwill, Frances Harris, Kate Screen, Hazel Morgan, Hywel David, Rhiannon Beken, Sonja Guenat, Olivier Rowan, Wendy Amour, Augustin |
author_facet | Candarlioglu, Pelin L. Dal Negro, Gianni Hughes, David Balkwill, Frances Harris, Kate Screen, Hazel Morgan, Hywel David, Rhiannon Beken, Sonja Guenat, Olivier Rowan, Wendy Amour, Augustin |
author_sort | Candarlioglu, Pelin L. |
collection | PubMed |
description | As an emerging hot topic of the last decade, Organ on Chip (OoC) is a new technology that is attracting interest from both basic and translational scientists. The Biochemical Society, with its mission of supporting the advancement of science, with addressing grand challenges that have societal impact, has included OoC into their agenda to review the current state of the art, bottlenecks and future directions. This conference brought together representatives of the main stakeholders in the OoC field including academics, end-users, regulators and technology developers to discuss and identify requirements for this new technology to deliver on par with the expectations and the key challenges and gaps that still need to be addressed to achieve robust human-relevant tools, able to positively impact decision making in the pharmaceutical industry and reduce overreliance on poorly predictive animal models. |
format | Online Article Text |
id | pubmed-9162452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Portland Press Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91624522022-06-07 Organ-on-a-chip: current gaps and future directions Candarlioglu, Pelin L. Dal Negro, Gianni Hughes, David Balkwill, Frances Harris, Kate Screen, Hazel Morgan, Hywel David, Rhiannon Beken, Sonja Guenat, Olivier Rowan, Wendy Amour, Augustin Biochem Soc Trans Review Articles As an emerging hot topic of the last decade, Organ on Chip (OoC) is a new technology that is attracting interest from both basic and translational scientists. The Biochemical Society, with its mission of supporting the advancement of science, with addressing grand challenges that have societal impact, has included OoC into their agenda to review the current state of the art, bottlenecks and future directions. This conference brought together representatives of the main stakeholders in the OoC field including academics, end-users, regulators and technology developers to discuss and identify requirements for this new technology to deliver on par with the expectations and the key challenges and gaps that still need to be addressed to achieve robust human-relevant tools, able to positively impact decision making in the pharmaceutical industry and reduce overreliance on poorly predictive animal models. Portland Press Ltd. 2022-04-29 2022-04-19 /pmc/articles/PMC9162452/ /pubmed/35437569 http://dx.doi.org/10.1042/BST20200661 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Articles Candarlioglu, Pelin L. Dal Negro, Gianni Hughes, David Balkwill, Frances Harris, Kate Screen, Hazel Morgan, Hywel David, Rhiannon Beken, Sonja Guenat, Olivier Rowan, Wendy Amour, Augustin Organ-on-a-chip: current gaps and future directions |
title | Organ-on-a-chip: current gaps and future directions |
title_full | Organ-on-a-chip: current gaps and future directions |
title_fullStr | Organ-on-a-chip: current gaps and future directions |
title_full_unstemmed | Organ-on-a-chip: current gaps and future directions |
title_short | Organ-on-a-chip: current gaps and future directions |
title_sort | organ-on-a-chip: current gaps and future directions |
topic | Review Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162452/ https://www.ncbi.nlm.nih.gov/pubmed/35437569 http://dx.doi.org/10.1042/BST20200661 |
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