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Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance

Evading immune destruction is one of the hallmarks of cancer. A key mechanism of immune evasion deployed by tumour cells is to reduce neoantigen presentation through down-regulation of the antigen presentation machinery. MHC-I and MHC-II proteins are key components of the antigen presentation machin...

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Detalles Bibliográficos
Autores principales: Balasubramanian, Adithya, John, Thomas, Asselin-Labat, Marie-Liesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162455/
https://www.ncbi.nlm.nih.gov/pubmed/35343573
http://dx.doi.org/10.1042/BST20210961

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