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Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don

For the first time, Cleisomeria lanatum (family: Orchidaceae) has been investigated for its phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties. All phytochemicals studied were identified in varying degrees during qualitative screening. In quantitative screening, a maximum of...

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Autores principales: Rahman, Minhajur, Surag, Abu Taleb, Begum, Roxy, Hossain Tusher, Md. Shakhuat, Huda, Mohammed Kamrul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162869/
https://www.ncbi.nlm.nih.gov/pubmed/35664371
http://dx.doi.org/10.1155/2022/5660527
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author Rahman, Minhajur
Surag, Abu Taleb
Begum, Roxy
Hossain Tusher, Md. Shakhuat
Huda, Mohammed Kamrul
author_facet Rahman, Minhajur
Surag, Abu Taleb
Begum, Roxy
Hossain Tusher, Md. Shakhuat
Huda, Mohammed Kamrul
author_sort Rahman, Minhajur
collection PubMed
description For the first time, Cleisomeria lanatum (family: Orchidaceae) has been investigated for its phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties. All phytochemicals studied were identified in varying degrees during qualitative screening. In quantitative screening, a maximum of 106.02 ± 0.08 mg/g alkaloids (root), 179.67 ± 8.83 mg/g phenols (stem), 17.34 ± 0.88 mg/g flavonoids (stem), 73.67 ± 1.76 mg/g tannins (stem), and 180.04 ± 0.02 μg/mL proteins (root) were detected. Antioxidant, anti-inflammatory, and thrombolytic properties were investigated using a free-radical scavenging assay, heat-induced albumin denaturation assay, and blood clotting inhibition assay. The root extracts had the most effective antioxidant (IC(50) = 67.98 μg/mL) and anti-inflammatory (IC(50) = 60.86 μg/mL) properties, whereas the stem extracts had the most effective thrombolytic property (IC(50) = 163.8 μg/mL). The bioactivities studied also had a significant positive relationship (r = 0.9; p  <  0.05) with the amount of phenolics and tannins.
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spelling pubmed-91628692022-06-03 Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don Rahman, Minhajur Surag, Abu Taleb Begum, Roxy Hossain Tusher, Md. Shakhuat Huda, Mohammed Kamrul Scientifica (Cairo) Research Article For the first time, Cleisomeria lanatum (family: Orchidaceae) has been investigated for its phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties. All phytochemicals studied were identified in varying degrees during qualitative screening. In quantitative screening, a maximum of 106.02 ± 0.08 mg/g alkaloids (root), 179.67 ± 8.83 mg/g phenols (stem), 17.34 ± 0.88 mg/g flavonoids (stem), 73.67 ± 1.76 mg/g tannins (stem), and 180.04 ± 0.02 μg/mL proteins (root) were detected. Antioxidant, anti-inflammatory, and thrombolytic properties were investigated using a free-radical scavenging assay, heat-induced albumin denaturation assay, and blood clotting inhibition assay. The root extracts had the most effective antioxidant (IC(50) = 67.98 μg/mL) and anti-inflammatory (IC(50) = 60.86 μg/mL) properties, whereas the stem extracts had the most effective thrombolytic property (IC(50) = 163.8 μg/mL). The bioactivities studied also had a significant positive relationship (r = 0.9; p  <  0.05) with the amount of phenolics and tannins. Hindawi 2022-05-26 /pmc/articles/PMC9162869/ /pubmed/35664371 http://dx.doi.org/10.1155/2022/5660527 Text en Copyright © 2022 Minhajur Rahman et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Rahman, Minhajur
Surag, Abu Taleb
Begum, Roxy
Hossain Tusher, Md. Shakhuat
Huda, Mohammed Kamrul
Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don
title Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don
title_full Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don
title_fullStr Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don
title_full_unstemmed Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don
title_short Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don
title_sort phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties of cleisomeria lanatum (lindl.) lindl. ex g. don
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162869/
https://www.ncbi.nlm.nih.gov/pubmed/35664371
http://dx.doi.org/10.1155/2022/5660527
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