Cargando…
Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don
For the first time, Cleisomeria lanatum (family: Orchidaceae) has been investigated for its phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties. All phytochemicals studied were identified in varying degrees during qualitative screening. In quantitative screening, a maximum of...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162869/ https://www.ncbi.nlm.nih.gov/pubmed/35664371 http://dx.doi.org/10.1155/2022/5660527 |
_version_ | 1784719803636776960 |
---|---|
author | Rahman, Minhajur Surag, Abu Taleb Begum, Roxy Hossain Tusher, Md. Shakhuat Huda, Mohammed Kamrul |
author_facet | Rahman, Minhajur Surag, Abu Taleb Begum, Roxy Hossain Tusher, Md. Shakhuat Huda, Mohammed Kamrul |
author_sort | Rahman, Minhajur |
collection | PubMed |
description | For the first time, Cleisomeria lanatum (family: Orchidaceae) has been investigated for its phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties. All phytochemicals studied were identified in varying degrees during qualitative screening. In quantitative screening, a maximum of 106.02 ± 0.08 mg/g alkaloids (root), 179.67 ± 8.83 mg/g phenols (stem), 17.34 ± 0.88 mg/g flavonoids (stem), 73.67 ± 1.76 mg/g tannins (stem), and 180.04 ± 0.02 μg/mL proteins (root) were detected. Antioxidant, anti-inflammatory, and thrombolytic properties were investigated using a free-radical scavenging assay, heat-induced albumin denaturation assay, and blood clotting inhibition assay. The root extracts had the most effective antioxidant (IC(50) = 67.98 μg/mL) and anti-inflammatory (IC(50) = 60.86 μg/mL) properties, whereas the stem extracts had the most effective thrombolytic property (IC(50) = 163.8 μg/mL). The bioactivities studied also had a significant positive relationship (r = 0.9; p < 0.05) with the amount of phenolics and tannins. |
format | Online Article Text |
id | pubmed-9162869 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-91628692022-06-03 Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don Rahman, Minhajur Surag, Abu Taleb Begum, Roxy Hossain Tusher, Md. Shakhuat Huda, Mohammed Kamrul Scientifica (Cairo) Research Article For the first time, Cleisomeria lanatum (family: Orchidaceae) has been investigated for its phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties. All phytochemicals studied were identified in varying degrees during qualitative screening. In quantitative screening, a maximum of 106.02 ± 0.08 mg/g alkaloids (root), 179.67 ± 8.83 mg/g phenols (stem), 17.34 ± 0.88 mg/g flavonoids (stem), 73.67 ± 1.76 mg/g tannins (stem), and 180.04 ± 0.02 μg/mL proteins (root) were detected. Antioxidant, anti-inflammatory, and thrombolytic properties were investigated using a free-radical scavenging assay, heat-induced albumin denaturation assay, and blood clotting inhibition assay. The root extracts had the most effective antioxidant (IC(50) = 67.98 μg/mL) and anti-inflammatory (IC(50) = 60.86 μg/mL) properties, whereas the stem extracts had the most effective thrombolytic property (IC(50) = 163.8 μg/mL). The bioactivities studied also had a significant positive relationship (r = 0.9; p < 0.05) with the amount of phenolics and tannins. Hindawi 2022-05-26 /pmc/articles/PMC9162869/ /pubmed/35664371 http://dx.doi.org/10.1155/2022/5660527 Text en Copyright © 2022 Minhajur Rahman et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Rahman, Minhajur Surag, Abu Taleb Begum, Roxy Hossain Tusher, Md. Shakhuat Huda, Mohammed Kamrul Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don |
title | Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don |
title_full | Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don |
title_fullStr | Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don |
title_full_unstemmed | Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don |
title_short | Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don |
title_sort | phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties of cleisomeria lanatum (lindl.) lindl. ex g. don |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162869/ https://www.ncbi.nlm.nih.gov/pubmed/35664371 http://dx.doi.org/10.1155/2022/5660527 |
work_keys_str_mv | AT rahmanminhajur phytochemicalantioxidantantiinflammatoryandthrombolyticpropertiesofcleisomerialanatumlindllindlexgdon AT suragabutaleb phytochemicalantioxidantantiinflammatoryandthrombolyticpropertiesofcleisomerialanatumlindllindlexgdon AT begumroxy phytochemicalantioxidantantiinflammatoryandthrombolyticpropertiesofcleisomerialanatumlindllindlexgdon AT hossaintushermdshakhuat phytochemicalantioxidantantiinflammatoryandthrombolyticpropertiesofcleisomerialanatumlindllindlexgdon AT hudamohammedkamrul phytochemicalantioxidantantiinflammatoryandthrombolyticpropertiesofcleisomerialanatumlindllindlexgdon |