Cargando…

Post Surgical Non-tuberculous Mycobacterium: A Case Series

Background There has been an increase in non-tuberculous mycobacteria (NTM) infection reports in humans. Surgeons are concerned about the link between them and surgical site infections. As a result, it has been challenging to determine just how common this illness is. A two-year study by the authors...

Descripción completa

Detalles Bibliográficos
Autores principales: Mhaske, Ashok N, Mhaske, Shubhangi, Harke, Sanjay, Jain, Arti, Patel, Jaswant, Mhaske, Sumedh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162884/
https://www.ncbi.nlm.nih.gov/pubmed/35663658
http://dx.doi.org/10.7759/cureus.24701
_version_ 1784719806962860032
author Mhaske, Ashok N
Mhaske, Shubhangi
Harke, Sanjay
Jain, Arti
Patel, Jaswant
Mhaske, Sumedh
author_facet Mhaske, Ashok N
Mhaske, Shubhangi
Harke, Sanjay
Jain, Arti
Patel, Jaswant
Mhaske, Sumedh
author_sort Mhaske, Ashok N
collection PubMed
description Background There has been an increase in non-tuberculous mycobacteria (NTM) infection reports in humans. Surgeons are concerned about the link between them and surgical site infections. As a result, it has been challenging to determine just how common this illness is. A two-year study by the authors examines the occurrence of NTM infections after different surgical procedures. Design and methods Researchers at a tertiary care hospital in central India performed this prospective study over two years. NTM was found in six of the 25 instances of post-surgical wound infections. Ziehl-Neelsen staining, Auramine O-Rhodamine fluorescence staining, Multiplex Real-Time PCR, and Genotyping were used to identify the species. Results M. fortuitum, M. chelonae and M.kansasii were isolated from discharge in 2 cases each respectively. NTM isolates evaluated for antibiotic susceptibility pattern were all sensitive to Clarithromycin (100%). One case with prolonged healing had to be intervened with amikacin along with clarithromycin. Conclusion NTM is an infection of uncommon nature which can occur following surgical procedures. Identification of these organisms through sensitive techniques and appropriate therapeutic regimen formulation must be done to tackle this growing menace in health care setups. 
format Online
Article
Text
id pubmed-9162884
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-91628842022-06-04 Post Surgical Non-tuberculous Mycobacterium: A Case Series Mhaske, Ashok N Mhaske, Shubhangi Harke, Sanjay Jain, Arti Patel, Jaswant Mhaske, Sumedh Cureus General Surgery Background There has been an increase in non-tuberculous mycobacteria (NTM) infection reports in humans. Surgeons are concerned about the link between them and surgical site infections. As a result, it has been challenging to determine just how common this illness is. A two-year study by the authors examines the occurrence of NTM infections after different surgical procedures. Design and methods Researchers at a tertiary care hospital in central India performed this prospective study over two years. NTM was found in six of the 25 instances of post-surgical wound infections. Ziehl-Neelsen staining, Auramine O-Rhodamine fluorescence staining, Multiplex Real-Time PCR, and Genotyping were used to identify the species. Results M. fortuitum, M. chelonae and M.kansasii were isolated from discharge in 2 cases each respectively. NTM isolates evaluated for antibiotic susceptibility pattern were all sensitive to Clarithromycin (100%). One case with prolonged healing had to be intervened with amikacin along with clarithromycin. Conclusion NTM is an infection of uncommon nature which can occur following surgical procedures. Identification of these organisms through sensitive techniques and appropriate therapeutic regimen formulation must be done to tackle this growing menace in health care setups.  Cureus 2022-05-03 /pmc/articles/PMC9162884/ /pubmed/35663658 http://dx.doi.org/10.7759/cureus.24701 Text en Copyright © 2022, Mhaske et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle General Surgery
Mhaske, Ashok N
Mhaske, Shubhangi
Harke, Sanjay
Jain, Arti
Patel, Jaswant
Mhaske, Sumedh
Post Surgical Non-tuberculous Mycobacterium: A Case Series
title Post Surgical Non-tuberculous Mycobacterium: A Case Series
title_full Post Surgical Non-tuberculous Mycobacterium: A Case Series
title_fullStr Post Surgical Non-tuberculous Mycobacterium: A Case Series
title_full_unstemmed Post Surgical Non-tuberculous Mycobacterium: A Case Series
title_short Post Surgical Non-tuberculous Mycobacterium: A Case Series
title_sort post surgical non-tuberculous mycobacterium: a case series
topic General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162884/
https://www.ncbi.nlm.nih.gov/pubmed/35663658
http://dx.doi.org/10.7759/cureus.24701
work_keys_str_mv AT mhaskeashokn postsurgicalnontuberculousmycobacteriumacaseseries
AT mhaskeshubhangi postsurgicalnontuberculousmycobacteriumacaseseries
AT harkesanjay postsurgicalnontuberculousmycobacteriumacaseseries
AT jainarti postsurgicalnontuberculousmycobacteriumacaseseries
AT pateljaswant postsurgicalnontuberculousmycobacteriumacaseseries
AT mhaskesumedh postsurgicalnontuberculousmycobacteriumacaseseries