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Herb-Induced Liver Injury: A Report on Two Australian Cases

Two 40-year-old males were admitted to our tertiary hepatology unit with acute hepatitis after presentation with generalized abdominal pain, nausea, and jaundice. There was no history of paracetamol overdose, and common viral and autoimmune causes were excluded through serology. Imaging and liver bi...

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Detalles Bibliográficos
Autores principales: Peri, Varun, Yu, Catherine, Vaz, Karl, Asadi, Khashayar, Grace, Josephine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162901/
https://www.ncbi.nlm.nih.gov/pubmed/35663668
http://dx.doi.org/10.7759/cureus.24686
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author Peri, Varun
Yu, Catherine
Vaz, Karl
Asadi, Khashayar
Grace, Josephine
author_facet Peri, Varun
Yu, Catherine
Vaz, Karl
Asadi, Khashayar
Grace, Josephine
author_sort Peri, Varun
collection PubMed
description Two 40-year-old males were admitted to our tertiary hepatology unit with acute hepatitis after presentation with generalized abdominal pain, nausea, and jaundice. There was no history of paracetamol overdose, and common viral and autoimmune causes were excluded through serology. Imaging and liver biopsy were performed with both investigations demonstrating non-specific features of hepatic inflammation. A history of herbal supplement use was elucidated in each patient, which was deemed to be the cause of liver injury in both men. Each patient recovered within two months of presentation following the withdrawal of the offending agent and supportive care.
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spelling pubmed-91629012022-06-04 Herb-Induced Liver Injury: A Report on Two Australian Cases Peri, Varun Yu, Catherine Vaz, Karl Asadi, Khashayar Grace, Josephine Cureus Gastroenterology Two 40-year-old males were admitted to our tertiary hepatology unit with acute hepatitis after presentation with generalized abdominal pain, nausea, and jaundice. There was no history of paracetamol overdose, and common viral and autoimmune causes were excluded through serology. Imaging and liver biopsy were performed with both investigations demonstrating non-specific features of hepatic inflammation. A history of herbal supplement use was elucidated in each patient, which was deemed to be the cause of liver injury in both men. Each patient recovered within two months of presentation following the withdrawal of the offending agent and supportive care. Cureus 2022-05-03 /pmc/articles/PMC9162901/ /pubmed/35663668 http://dx.doi.org/10.7759/cureus.24686 Text en Copyright © 2022, Peri et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Peri, Varun
Yu, Catherine
Vaz, Karl
Asadi, Khashayar
Grace, Josephine
Herb-Induced Liver Injury: A Report on Two Australian Cases
title Herb-Induced Liver Injury: A Report on Two Australian Cases
title_full Herb-Induced Liver Injury: A Report on Two Australian Cases
title_fullStr Herb-Induced Liver Injury: A Report on Two Australian Cases
title_full_unstemmed Herb-Induced Liver Injury: A Report on Two Australian Cases
title_short Herb-Induced Liver Injury: A Report on Two Australian Cases
title_sort herb-induced liver injury: a report on two australian cases
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162901/
https://www.ncbi.nlm.nih.gov/pubmed/35663668
http://dx.doi.org/10.7759/cureus.24686
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