Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main protease

The COVID-19 posed a serious threat to human life and health, and SARS-CoV-2 M(pro) has been considered as an attractive drug target for the treatment of COVID-19. Herein, we report 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 M(pro) developed by in...

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Detalles Bibliográficos
Autores principales: Dou, Xiaodong, Sun, Qi, Xu, Guofeng, Liu, Yameng, Zhang, Caifang, Wang, Bingding, Lu, Yangbin, Guo, Zheng, Su, Lingyu, Huo, Tongyu, Zhao, Xinyi, Wang, Chen, Yu, Zhongtian, Song, Song, Zhang, Liangren, Liu, Zhenming, Lai, Luhua, Jiao, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162962/
https://www.ncbi.nlm.nih.gov/pubmed/35688005
http://dx.doi.org/10.1016/j.ejmech.2022.114508

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