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Incidental cardiac findings on somatostatin receptor PET/CT: What do they indicate and are they of clinical relevance?
We present the case of a 47-year-old man with a history of recurrent episodes of frontal headache, fever, and chest discomfort as well as longstanding, difficult to treat arterial hypertension. Clinical work-up revealed the unexpected finding of an underlying pheochromocytoma as well as recent “sile...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163016/ https://www.ncbi.nlm.nih.gov/pubmed/33502695 http://dx.doi.org/10.1007/s12350-021-02526-9 |
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author | Bobbio, Emanuele Dudás, Anna Bergström, Anders Esposito, Daniela Angerås, Oskar Taha, Amar van Essen, Martijn Björkenstam, Marie Karason, Kristjan Bollano, Entela Bergh, Niklas Polte, Christian L. |
author_facet | Bobbio, Emanuele Dudás, Anna Bergström, Anders Esposito, Daniela Angerås, Oskar Taha, Amar van Essen, Martijn Björkenstam, Marie Karason, Kristjan Bollano, Entela Bergh, Niklas Polte, Christian L. |
author_sort | Bobbio, Emanuele |
collection | PubMed |
description | We present the case of a 47-year-old man with a history of recurrent episodes of frontal headache, fever, and chest discomfort as well as longstanding, difficult to treat arterial hypertension. Clinical work-up revealed the unexpected finding of an underlying pheochromocytoma as well as recent “silent” myocardial infarction. Our case highlights the importance of paying attention to incidental cardiac findings on somatostatin receptor positron emission tomography/computed tomography, as routinely performed in patients with clinically suspected neuroendocrine tumors. These incidental cardiac findings cannot only indicate a primary or secondary (metastatic) neuroendocrine tumor, but also areas of myocardial inflammation, as somatostatin receptors cannot only be found on the majority of neuroendocrine tumors, but also among other tissues on the surface of activated macrophages and lymphocytes. The detection of myocardial inflammation is of clinical importance and its underlying etiology should be evaluated to prompt eventual necessary treatment, as it is a potential driving force for cardiac remodeling and poor prognosis. |
format | Online Article Text |
id | pubmed-9163016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-91630162022-06-05 Incidental cardiac findings on somatostatin receptor PET/CT: What do they indicate and are they of clinical relevance? Bobbio, Emanuele Dudás, Anna Bergström, Anders Esposito, Daniela Angerås, Oskar Taha, Amar van Essen, Martijn Björkenstam, Marie Karason, Kristjan Bollano, Entela Bergh, Niklas Polte, Christian L. J Nucl Cardiol Case Presentation Corner We present the case of a 47-year-old man with a history of recurrent episodes of frontal headache, fever, and chest discomfort as well as longstanding, difficult to treat arterial hypertension. Clinical work-up revealed the unexpected finding of an underlying pheochromocytoma as well as recent “silent” myocardial infarction. Our case highlights the importance of paying attention to incidental cardiac findings on somatostatin receptor positron emission tomography/computed tomography, as routinely performed in patients with clinically suspected neuroendocrine tumors. These incidental cardiac findings cannot only indicate a primary or secondary (metastatic) neuroendocrine tumor, but also areas of myocardial inflammation, as somatostatin receptors cannot only be found on the majority of neuroendocrine tumors, but also among other tissues on the surface of activated macrophages and lymphocytes. The detection of myocardial inflammation is of clinical importance and its underlying etiology should be evaluated to prompt eventual necessary treatment, as it is a potential driving force for cardiac remodeling and poor prognosis. Springer International Publishing 2021-01-27 2022 /pmc/articles/PMC9163016/ /pubmed/33502695 http://dx.doi.org/10.1007/s12350-021-02526-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Case Presentation Corner Bobbio, Emanuele Dudás, Anna Bergström, Anders Esposito, Daniela Angerås, Oskar Taha, Amar van Essen, Martijn Björkenstam, Marie Karason, Kristjan Bollano, Entela Bergh, Niklas Polte, Christian L. Incidental cardiac findings on somatostatin receptor PET/CT: What do they indicate and are they of clinical relevance? |
title | Incidental cardiac findings on somatostatin receptor PET/CT: What do they indicate and are they of clinical relevance? |
title_full | Incidental cardiac findings on somatostatin receptor PET/CT: What do they indicate and are they of clinical relevance? |
title_fullStr | Incidental cardiac findings on somatostatin receptor PET/CT: What do they indicate and are they of clinical relevance? |
title_full_unstemmed | Incidental cardiac findings on somatostatin receptor PET/CT: What do they indicate and are they of clinical relevance? |
title_short | Incidental cardiac findings on somatostatin receptor PET/CT: What do they indicate and are they of clinical relevance? |
title_sort | incidental cardiac findings on somatostatin receptor pet/ct: what do they indicate and are they of clinical relevance? |
topic | Case Presentation Corner |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163016/ https://www.ncbi.nlm.nih.gov/pubmed/33502695 http://dx.doi.org/10.1007/s12350-021-02526-9 |
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