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Mistargeting of aggregation prone mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes

Mitochondrial protein import in the parasitic protozoan Trypanosoma brucei is mediated by the atypical outer membrane translocase, ATOM. It consists of seven subunits including ATOM69, the import receptor for hydrophobic proteins. Ablation of ATOM69, but not of any other subunit, triggers a unique q...

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Detalles Bibliográficos
Autores principales:	Dewar, Caroline E., Oeljeklaus, Silke, Mani, Jan, Mühlhäuser, Wignand W. D., von Känel, Corinne, Zimmermann, Johannes, Ochsenreiter, Torsten, Warscheid, Bettina, Schneider, André
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163028/ https://www.ncbi.nlm.nih.gov/pubmed/35654893 http://dx.doi.org/10.1038/s41467-022-30748-z

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