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Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate

The formation of membraneless organelles can be a proteotoxic stress control mechanism that locally condenses a set of components capable of mediating protein degradation decisions. The breadth of mechanisms by which cells respond to stressors and form specific functional types of membraneless organ...

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Detalles Bibliográficos
Autores principales: Carrettiero, Daniel C., Almeida, Maria C., Longhini, Andrew P., Rauch, Jennifer N., Han, Dasol, Zhang, Xuemei, Najafi, Saeed, Gestwicki, Jason E., Kosik, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163039/
https://www.ncbi.nlm.nih.gov/pubmed/35654899
http://dx.doi.org/10.1038/s41467-022-30751-4