Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants

The effects of adjuvants for increasing the immunogenicity of influenza vaccines are well known. However, the effect of adjuvants on increasing the breadth of cross-reactivity is less well understood. In this study we have performed a systematic screen of different toll-like receptor (TLR) agonists,...

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Detalles Bibliográficos
Autores principales: Hernandez-Davies, Jenny E., Dollinger, Emmanuel P., Pone, Egest J., Felgner, Jiin, Liang, Li, Strohmeier, Shirin, Jan, Sharon, Albin, Tyler J., Jain, Aarti, Nakajima, Rie, Jasinskas, Algimantas, Krammer, Florian, Esser-Kahn, Aaron, Felgner, Philip L., Nie, Qing, Davies, D. Huw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163070/
https://www.ncbi.nlm.nih.gov/pubmed/35654904
http://dx.doi.org/10.1038/s41598-022-12727-y

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