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Artificial neural networks enable genome-scale simulations of intracellular signaling

Mammalian cells adapt their functional state in response to external signals in form of ligands that bind receptors on the cell-surface. Mechanistically, this involves signal-processing through a complex network of molecular interactions that govern transcription factor activity patterns. Computer s...

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Detalles Bibliográficos
Autores principales:	Nilsson, Avlant, Peters, Joshua M., Meimetis, Nikolaos, Bryson, Bryan, Lauffenburger, Douglas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163072/ https://www.ncbi.nlm.nih.gov/pubmed/35654811 http://dx.doi.org/10.1038/s41467-022-30684-y

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